IE Freezes Constantly, Multiple Iexplore.exe*32 Running?

Fo the last few days, Internet explorer stops working all of the time. When this happens, no desktop icons work. Sometimes, I can use task manager to shut down instances of iexplore.exe*32 and it works again for a while. Sometimes, I am not allowed to close the instances with task manager as it says operationdenied.Malwarebytes returns 0 issues. I tried MS safety scanner and that also found nothing.I assume there is a virus or trojan at work here but I really don't know what else to do