Maintenance :: Windows 8 Computer Freezes While Using CCleaner?

After two refresh and one clean install of Windows 8 within a two-week period, my computer freezes while I'm running CCleaner. It always stops at the same file:

CUserAppDataLocalTemp\_ME149482PyWinTypes26.dll

First few minutes, I can still use my computer, but after that, I cannot print, cannot open Task Manager, cannot shut down the computer. After numerous attempts, I'm able to close CCleaner, but my computer remains frozen.