Assign Static IP To Both Wired And Wireless Adapters?

In my XP days I would assign each of my laptop's network adapters (wired and wireless) its own static IP address. I did this to make it easier to manage things like opening certain ports when using the laptop for gaming over the wired connection only.

Now that I have an all Vista home network consisting of a laptop and a desktop both with Vista Home Premium I am running into trouble assigning these static IPs on the laptop. The primary connection is the wireless and i use the wired connection to game or to transfer files across the network. When I go to set the IP on the wired connection I get the message: "Warning: Multiple default gateways are intended to provide redundancy to a single network such as and Intranet or the Internet. They will not function properly when the gateways are on two separate, disjoint networks (such as one on your intranet and one on the Internet). Do you want to save this configuration?".................