Getting Message "The Request Could Not Be Performed Because Of An I/O Device Error"?

I have searched here and googled this error, and while I have found similar, nothing that same as this.I have been unable to update my Itunes, so after some research I realized it was the failure to update quicktime durring the Itunes update that was really happening. I have tried multiple things to fix this, all of which have been unsuccessful. Nothing would tell me why, just that quicktime failed to update.

My next step was to uninstall quicktime, this also failed with no reason why. So I attempted to Manually delete all quicktime files, and then run tuneup utilities to remove all registry entries. However when doing this I found I could delete all files, except the folder c:Program FilesQuickTimeQTSystem QuickTimeStreaming.Resourcesde.lproj . When I try I get the below error message Code: Cannot delete de.lproj: The request could not be performed because of an I/O device error