Programs Not Launching After Restart?

every now and then my work PC restarts itself over night and when I come into work in the morning and find this. Every time this happens, the bulk of my programs won't launch - apart from IE, file explorer and native applications like the Task Manager. It's very strange - I try to launch an application, it attempts to load then seems to die, although in the task manager I can always see each instance of the program I've tried to start, with very low memory footprint.his has just happened to me again this morning, and after an hour or so of rebooting, eventually the applications have started working again, without any change having been made by me. I have run a defrag and disk check and also updated Windows 7 with all available updates, but the issue remains. I also switched the firewall off and still had the same problem.