After Putting In New Optical / Computer Won't Start

I know quite a bit about computers, and this is my custom build. I upgraded my mobo/cpu/ram in June, but my budget ran short of getting an optical which used SATA. yesterday was my birthday and I was able to purchase myself a new optical drive. The problem is. Last night I opened my case, put it in, power and data cables and then my computer won't boot correctly. This also happened when I first upgraded, but the problem isn't being solved this time. My keyboard only lights up when I flip the PSU power switch on the back. When I boot up I get no lights on my keyboard, my monitor light stays orange, all fans, etc turn on inside the case. I tried unplugging the new drive and starting it, with it's previous configuration, but that will not work. I have tried spamming the key to get into the BIOS, which is what worked in June when I was getting no video.