Programs Won't Run After Windows Updates

Ad our work we installed 10 new PC HP Z400 workstations with windows 7 64bits, we installed Office 2007 small business and Autocad 2011, Sophos anti virus.

After our install every thing seems to work fine computers are set in network and login to server windows 2003, get mail from exchange 2003. and get windows updates from the server 1 day in the week, for the updates we aprove in the windows update service on the server.

but some how the 10x 64bits windows 7 machines dont hold themselfs to update shedul from ones a week from the server, on the client you can't adjust the settings for updating because its locked from out the server but it will update every day if needed we have 3x 32bits windows 7 machines who dont have this problem, the rest of our machines run on windows XP.

the updating shedule isn't a big problem but every time we get an update the programs we use wont work any more they fail in starting up especialy Autocad and Office 2007 wont start Outlook starts up and runs but when we open an other mail then where the program starts in the program fails to work and we have to force it to close reboot the machine 1-5 times to get the programs working, after that it works perfect till a next update from windows