It's Mass Hysteria! Temp Files Found That Don't Exist - Spyware Removers Gone Wild

I was running The Cleaner for the first time and it found several files to delete that I can't seem to find on my system. It shows them to be temp files but I like to be sure so I went searching for them. They're not visible. I've enabled the see all files so it should be there. But it's not. I did however find these files and am wondering why they would be found under IE5 which I haven't used now since the rebuild. And I don't think that was even under this hard drive! Is it safe to let it delete, or is that stuff I shouldn't delete?
C: Documents & Settings: User: Local Settings: Temporary Internet Files: Content.IE5: 3I1TVRX8, 4NM0HAS5, 7D8UQMOE, index.dat

Also I'm concerned by this message that keeps coming up saying Browser Help Objects have been detected - The following BHO has been added to your system: {BDF3E430~B101~42AD~A544~FADC6B084872} and I can either remove it or keep it. I ran a program called BHODemon to check it out and it found several BHO's but they were all legit. Could this all just be from a conflict from having SpywareGuard and Spybot both on my machine? Spybot seem to be going crazy asking if I want to change things. I can't stop them from popping back up when I close one another comes up. The error messages are always different too which is really confusing.