CD's Not Recognizable By PC

You have been so helpful in the past and I am seeking help again. My husband understand this a little more than I so I had him type our concern below. Thank you in advance I hope you have a solution to our problem. Had Windows98

1.(E: Drive) CDROM that came with PC
2.(D: Drive) Installed a 2nd CDROM (TDK) With Read/Write Capabilities (Used Roxio software)
3.(F: Drive) Installed an adapter for about 4 USB ports to upload pictures

Then we installed WindowsXP, Professional Edition.
1.The CDROM that came with PC still worked
2.The Installed CDROM could at first create music CD's but not with the Roxio Software
3.We could not create data CD's
4.We could upload pictures from digital camera for a while.
5.Now, for some reason, the D:, E: or the F: drives are not recognized. When a CD is placed into the D: or E: drive, a message pops up to the screen to �enter a CD into the drive�. We went into the Device Manager in the Control Panel, but it shows that all of the drives are working properly. I�m thinking that it might have something to do with the Windows Registry, but that�s scary. And since it�s WindowsXP, the boot up disk is actually the CD and that�s no good, because the CD player is inoperable.